METHYL THIAZOLE-5-CARBOXYLATE

METHYL THIAZOLE-5-CARBOXYLATE - Names and Identifiers

Name	Methyl 5-thiazolecarboxylate
Synonyms	RARECHEM AL BF 1261 Methyl 5-thiazolecar METHYL 5-THIAZOLECARBOXYLATE Methyl 5-thiazolecarboxylate METHYL THIAZOLE-5-CARBOXYLATE methyl 1,3-thiazole-5-carboxylate methyl 1,3-thiazole-4-carboxylate Thiazole-5-carboxylic acid methyl ester 5-Thiazolecarboxylic acid, methyl ester
CAS	14527-44-7
InChI	InChI=1/C5H5NO2S/c1-8-5(7)4-2-9-3-6-4/h2-3H,1H3

METHYL THIAZOLE-5-CARBOXYLATE - Physico-chemical Properties

Molecular Formula	C5H5NO2S
Molar Mass	143.16
Density	1.45
Melting Point	68-69°C
Boling Point	87-90°C (10 mmHg)
Flash Point	86.8°C
Vapor Presure	0.117mmHg at 25°C
pKa	0.80±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.539
MDL	MFCD03788563

METHYL THIAZOLE-5-CARBOXYLATE - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Note	Harmful

METHYL THIAZOLE-5-CARBOXYLATE - Introduction

Methyl 5-thiazolecarboxylate is an organic compound with the chemical formula C6H5NO2S. The following is an introduction to the nature, use, formulation and safety information of Methyl 5-thiazolecarboxylate:

Nature:
Methyl 5-thiazolecarboxylate is a colorless or light yellow liquid with a special sulfide odor. It can be dissolved in organic solvents such as ethanol and dimethylformamide, and is insoluble in water.

Use:
Methyl 5-thiazolecarboxylate has a wide range of applications in drug synthesis. It is an important intermediate for the synthesis of some anticancer drugs and other physiologically active compounds. In addition, it can also be used as a catalyst or solvent in organic synthesis.

Method:
The preparation of Methyl 5-thiazolecarboxylate can be obtained by reacting Methyl acetate and sodium thiosulfate. A specific method is to dissolve sodium thiosulfate and methyl ethyl ester in an organic solvent, and then add sodium carbonate or potassium carbonate. After the reaction is carried out, the product is obtained by crystallization or distillation.

Safety Information:
Methyl 5-thiazolecarboxylate is less harmful to the human body under normal conditions. However, it is a flammable liquid, and care should be taken to avoid exposure to open flames and high temperatures. During operation, attention should be paid to protective measures, such as wearing protective gloves and goggles. At the same time, it should be stored in a sealed container, away from fire and oxidizing agents.

Please note that when using and handling Methyl 5-thiazolecarboxylate, you should follow the correct laboratory safety operating guidelines and consult relevant professionals.

Last Update：2024-04-09 21:11:58